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Devoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi R, Fong L, Anderson MS. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. J Exp Med. 2006 Nov 20;
Nuyten DS, Kreike B, Hart AA, Chi JT, Sneddon JB, Wessels LF, Peterse H, Bartelink H, Brown PO, Chang HY, Van de Vijver MJ. Predicting a local recurrence after breast-conserving therapy by gene expression profiling. Breast Cancer Research. 2006 Oct 30;8(5):R62
Huang, W, Chang, HY, Fei, T, Wu, H, Chen, YG. GSK3beta mediates suppression of cyclin D2 expression by tumor suppressor PTEN. Oncogene Advance online publication, 9 October 2006; doi:10.1038/sj.onc.1210033.
Sneddon, J.B., H.H. Zhen, K. Montgomery, M. vd Rijn, A.D.Tward, R. West, H. Gladstone, H.Y. Chang, G.S. Morganroth, A.E. Oro, P.O. Brown BMP antagonist Gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proc. Natl Acad. Sci. USA 2006 103, 14842-14847
Rinn, JL, Bondre, C, Gladstone, HB, Brown, PO, Chang, HY Anatomic demarcation by positional variation in fibroblast gene expression programs. PLoS Genetics 2006 2(7): e119.
Ray, S, Atkuri, KR, Deb-Basu, D, Adler, AS, Chang, HY, Herzenberg, LA, Felsher, DW MYC Can Induce DNA Breaks In vivo and In vitro Independent of Reactive Oxygen Species. Cancer Research 2006 Jul;66(13):6598-6605.
Adler AS and Chang, HY From Description to Causality: Mechanisms of Gene Expression Signatures in Cancer. Cell Cycle 2006 Jun;5(11):1148-1151.
Adler AS, Lin M, Horlings H, Nuyten DSA, van de Vijver M, Chang, HY. Genetic regulators of large-scale transcriptional signatures in cancer Nature Genetics 2006 Apr;38(4):421-430.
2005
Wong, DJ and Chang, HY |
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| Pubmed | JID |
Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sorlie T, Dai H, He YD, Van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ.
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
Proc Natl Acad Sci USA 2005 Mar 8; 102(10):3738-3743.
| Pubmed | PNAS | Web Supplement |
Before 2005
Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO.
Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.
PLoS Biol 2004 Feb; 2(2):E7.
| Pubmed | PLoS Biology | Web Supplement |
Chang, HY, Thomson, JA, Chen, X.
Microarray analysis of stem cells and differentiation.
Handbook of Adult and Fetal Stem Cells. 2004. R. Lanza et al., Eds. (San Diego: Academic Press).
Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO.
Endothelial cell diversity revealed by global expression profiling.
Proc Natl Acad Sci U S A 2003 Sep 16; 100(19): 10623-10628.
| Pubmed | PNAS | Web Supplement |
Chi, JT, Chang, HY, Wang, NN, Chang, DS, Dunphy, N, Brown, PO.
Genome-wide view of gene silencing by small interfering RNAs.
Proc Natl Acad Sci USA 2003, 100, 6343-6346. Recommended by Faculty of 1000.
| Pubmed | PNAS |
Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, Brown PO.
Diversity, topographic differentiation, and positional memory in human fibroblasts.
Proc Natl Acad Sci USA 2002 Oct 1; 99(20): 12877-12882.
| Pubmed | PNAS | Web Supplement |
Chang, HY and Yang X.
Proteases for cell suicide: regulation and functions of caspases. Microbiol Molec Biol Review 2000, 64, 821-846.
Chang, HY, Yang, X, Baltimore, D.
Dissecting Fas signaling with an altered specificity death-domain mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation.
Proc Natl Acad Sci USA 1999, 96, 1252-1256.
Chang, HY, H Nishitoh, X Yang, H Ichijo, and D Baltimore.
Activation of Apoptosis Signal-regulating Kinase 1 (ASK1) by the adapter protein Daxx.
Science 1998, 281, 1860-1863.
Yang, X., H.Y. Chang, and D. Baltimore.
Essential role of CED-4 oligomerization in CED-3 activation and apoptosis.
Science 1998, 281, 1355-1357.
Yang, X., H.Y. Chang, and D. Baltimore
Autoproteolytic activation of pro-caspases by oligomerization.
Molecular Cell 1998, 1, 319-325.
Yang, X., R. Khosravi-Far, H.Y. Chang, and D. Baltimore.
Daxx, a novel Fas-binding protein that activates JNK and apoptosis.
Cell 1997, 89, 1067-1076.
Chang, H.Y., K. Takei, A.M. Sydor, T. Born, F. Rusnak, and D.G. Jay.
Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin.
Nature 1995, 376, 686-690.
DiComo, C.J., H.Y. Chang, and K.T. Arndt. (1995)
Activation of CLN1 and CLN2 G1 cyclin expression by BCK2.
Mol Cell Biol 1995, 15, 1835-1846.
Zydowsky, L.D., F.A. Etzkorn, H.Y. Chang, S.B. Ferguson, L.A. Stoltz, S.I. Ho, and C.T. Walsh.
Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition.
Protein Science 1992, 1, 1092-1099.
Swanson, S.K.-H., T. Born, L.D. Zydowsky, H. Cho, H.Y. Chang, C.T. Walsh, and F. Rusnak. (1992)
Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilin A and B.
Proc Natl Acad Sci USA 1992, 89, 3741-3745.