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Chang Lab Alumni
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John L. Rinn, Ph.D. Postdoc, 2004-2007.
John was Howard's first postdoc. John studied positional identity in skin and discovered long noncoding RNAs in the HOX loci that regulate chromatin states. He was a Damon Runyon Fellow, and became Assistant Professor of Pathology at Harvard Medical School and Associate Member of the Broad Institute of MIT and Harvard.
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Adam S. Adler, Ph.D. Graduate Student, 2005-2008.
Adam was Howard's first Ph.D. student. Adam studied mechanisms underlying gene expression changes in cancer and aging. He identified novel therapeutic targets for aggressive human breast cancers, and he discovered a global regulator of mammalian aging that, upon its blockade, can reverse several effects of aging. He became a postdoc in Gill Bejerano's lab at Stanford University studying computational biology.
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Helen Liu, Medical Student, 2005-2008.
Helen was a Stanford medical student and received a Med Scholar award to pursue research in Howard's lab. She studied the transcriptional programs of cellular quiescence and cancer stem cells. Helen became a Dermatology resident at Oregon Health Sciences University.
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Jordon Wang, Ph.D. Graduate Student, 2005-2009
Jordon was another founding member of the lab. Jordon characterized HOTAIR, the first noncoding RNA that regulates chromatin state in trans, and study the stability of HOX gene expression programs in human fibroblasts. He also helped to discover and characterize UTX, the long sought after histone H3 lysine 27 demethylase.”
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Raj Gupta, M.D., Ph.D. Postdoc, 2007-2010
Raj was a post-doctoral fellow in Howard's lab. He studied the role of lincRNAs in modulating the epigenome during cancer development. He is currently working as a co-founder of a start up enterprise in the health care space and practices as a dermatologist in the Bay Area part-time. He remains affiliated with Stanford as a Clinical Assistant Professor of Dermatology.
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David J. Wong, M.D., Ph.D. Postdoc, 2006-2010
Dave was a postdoctoral fellow in the lab studying: 1) mechanisms that underlie cancer stem cells, 2) genomic signatures that predict therapeutic response in human cancer, and 3) the role of ncRNAs in the cell cycle. He became an Assistant Professor of Dermatology at Stanford as well as the co-founder of a health care technology company.
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Tiara Kawahara Ph.D. Student 2006-2010
Tiara received her B.S. from Northwestern and joined the lab as a Stanford Cancer Biology Ph.D. student. She discovered the connection between NF-kB, Sirt6, and aging in collaborated with the Chua lab. She is now a consultant specializing in life sciences at LEK Consulting.
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Kristine Ong
Undergraduate Student
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Miao-Chih Tsai, Ph.D Postdoc
Miao came to the Chang lab after Ph.D. at Cambridge University with Prof. Julie Ahringer. Miao was a Susan Komen Fellow, and discovered the modular organization of lincRNAs for controlling chromatin state. She became an editor at Molecular Cell.
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Ashley Kern Koegel
M.D., Ph.D Student
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Angeline Protacio, Life Science Research Assistant
Angeline was Howard's first Lab Technician. She worked with Kevin Wang to help characterize the HOTTIP lncRNA, and also explored how DNA binding site mutations in Ash2L affect HOX gene expression. She is now pursuing an MPH in Epidemiology at the Mailman School of Public Health at Columbia University.
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Yul Yang
M.D., Ph.D Student
Yul received his B.S. from Yale and came to the Stanford M.D.-Ph.D program. He helped to characterize HOTTIP, a lncRNA that mediates active chromatin, and studied its mechanism of function. Yul went back to Stanford Medical School to complete his medical studies.
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Kevin C, Wang M.D., Ph.D
Postdoc 2008-2012
Kevin came to the Chang lab after completing his dermatology residency at UCSF, and elucidated the molecular mechanisms underlying how long noncoding RNAs regulate active chromatin domains. He recently started his own research program as an Assistant Professor of Dermatology at Stanford.
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Tiffany Hung
Ph.D. Student
Tiffany received her B.S. at Stanford and joined the Cancer Biology Ph.D. program. Tiffany discovered new families of lncRNAs transcribed from cell cycle promoters and in response to DNA damage. These lncRNAs have important roles in cell cycle regulation and damage signaling. Tiffany received the NSF and NSDEG Graduate Fellowships. She is now a postdoctoral fellow at Genentech.
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Zhengqing Ouyang, Ph.D
Joint postdoc with Prof. Mike Snyder
Zhengqing was a joint postdoctoral fellow in the Chang and Snyder labs. He developed SeqFold, a computational algorithm for accurate reconstruction of RNA structure based on high throughput sequencing data. Zhengqing is now Assistant Professor at the Jackson Laboratory for Genomic Medicine.
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Ashwin Peres-da-Silva
Undergraduate Student
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Megan Mikhail
Undergraduate Student
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Ray Herrman,
Admin Associate
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Nicole Rapicavoli, Ph.D
Postdoc, 2009-2013
Nicole received her Ph.D. at Johns Hopkins University with Prof. Seth Blackshaw. In the Chang lab, Nicole studied the dynamics of gene expression during aging. She discovered a family of lncRNAs that are regulated by inflammatory signaling pathways through NF-kB.
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Yue Wan
Graduate Student, 2008-2013
Yue received her B.S. from UCSD and joined the Stanford Cancer Biology Ph.D. program with support from the A-STAR program. Yue developed the first methods to measure RNA structure and folding energies genome-wide, and described the first "RNA structurome". She became the first GIS Fellow (junior group leader) at Genome Institute of Singapore.
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